Samodzielna Pracownia Epigenetyki Klinicznej
Siedziba jednostki:
Unii Lubelskiej 1, 71-281 Szczecin.
Kierownictwo:
- dr hab. n. med., prof. PUM Tomasz K. Wojdacz - group leader
- dr n. med. Olga Taryma-Leśniak
The Independent Clinical Epigenetics Laboratory
Was founded in 2019, with a grant from The National Agency for Academic Exchange. Our research primarily focuses on translational epigenetics. Specifically, we are interested in epigenetic mechanisms of disease development as well as applications of epigenetic biomarkers in the assessment of disease predisposition, early disease detection, and personalized medicine.
We are looking for both scientists and students interested in translational epigenetics to work or collaborate with us. If you have any questions, write us.
Clinical Epigenetics International Conference - CLEPIC
The Independent Clinical Epigenetics Laboratory is an organizer of CLEPIC. For more information see:
International Society for Molecular and Clinical Epigenetics – iSMoClEp
The Independent Clinical Epigenetics Laboratory is a part of iSMoClEp. For more information see:
Funding/grants
- The Polish National Agency for Academic Exchange - NAWA
- NCN PRELUDIUM BIS
- NCN OPUS
- European Regional Development Fund of the West Pomeranian Province
- ERA PerMed IMAGene
Software developed by us
- eDAVE - extension of GDC Data Analysis, Visualization, and Exploration Tools web app is avaiable from here.
Lab members:
- Olga Taryma-Leśniak, PhD, contakt: olga.taryma-lesniak[at]pum.edu.pl
- Katarzyna Sokołowska MSc, PhD-student, contakt: katarzyna.sokolowska[at]pum.edu.pl
- Jan Bińkowski MSc, Bioinformatician, contakt: jan.binkowski[at]pum.edu.pl
- Patrycja Przybyłowicz - MSc, Bioinformatician
- Melanie Staszewski - Fulbright student
- Konrad Borowski - MD student
- Szymon Retfinski - MD student
Working with us:
- Hubert Rola - MD
- Jakub Rosik - MD
- Filip Machaj - MD
- Tomasz Falgowski - MD
- Magdalena Bednarek-Jędrzejek - MD
- Malgorzata Poniatowska - MD student
- Hanna Maciejowska - MSc student
- Dawid Bierbasz - MSc student
- Jacek Antoniewski - MSc student
- Denis Myszak - MD student
- Zuzanna Adamczyk - MSc student
- Mateusz Cejko - MD student
Recent papers:
- eDAVE – Extension of GDC data analysis, visualization, and exploration tools
- Identified in blood diet-related methylation changes stratify liver biopsies of NAFLD patients according to fibrosis grade
- Clinical significance of DNA methylation in chronic lymphocytic leukemia patients: results from 3 UK clinical trials
- Epigenetic activation of antiviral sensors and effectors of interferon response pathways during SARS-CoV-2 infection
- WHO CNS5 2021 classification of gliomas: a practical review and road signs for diagnosing pathologists and proper patho-clinical and neuro-oncological cooperation
- Long-Term Treatment with Bortezomib Induces Specific Methylation Changes in Differentiated Neuronal Cells
- Methylation levels assessment with Methylation-Sensitive High-Resolution Melting (MS-HRM)
- IGHV-associated methylation signatures more accurately predict clinical outcomes of chronic lymphocytic leukemia patients than IGHV mutation load
- Bortezomib induces methylation changes in neuroblastoma cells that appear to play a significant role in resistance development to this compound
- Short history of 5-methylcytosine: from discovery to clinical applications
- Current status of development of methylation biomarkers for in vitro diagnostic IVD applications
Read more about our us and what we do in non-scientific language:
- https://www.newsweek.pl/zdrowie-i-nauka/zdrowie/tomasz-k-wojdacz-mozemy-wyhamowac-przyspieszone-starzenie-rozmowa/xgg9qqg
- https://www.newsweek.pl/zdrowie-i-nauka/nauka/tajemnice-dziedziczenia-leki-lub-stres-moga-miec-wplyw-na-dziedziczenie/hzsswrt
- https://www.youtube.com/watch?v=ut2PFsl_yMI&ab_channel=Bio-TechMedia
- https://www.youtube.com/watch?v=17PxKHw020o&ab_channel=GazetaWyborcza
- https://pap-mediaroom.pl/nauka-i-technologie/dr-hab-tomasz-wojdacz-epigenetyka-dziedzina-ktora-odmieni-medycyne
- https://naukawpolsce.pl/aktualnosci/news%2C92011%2Cdr-hab-tomasz-wojdacz-w-przyszlosci-bedziemy-chodzic-do-lekarza-z-paszportem
- https://naukawpolsce.pl/aktualnosci/news,79845,epignetyczne-zmiany-chorobowe-mozna-odwrocic.html
- https://naukawpolsce.pl/aktualnosci/news,79844,znalezc-dna-raka-krazace-w-plynach-ustrojowych.html
- https://pap-mediaroom.pl/nauka-i-technologie/prof-wojdacz-spowolnienie-starzenia-dzieki-epigenetyce-przyszlosc-medycyny
- https://pap-mediaroom.pl/nauka-i-technologie/prof-wojdacz-naukowiec-musi-byc-mobilny
